After the Kidney Transplant - The Patients and Their - download pdf or read online

By Jorge Ortiz, Jason André

ISBN-10: 9533078073

ISBN-13: 9789533078076

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In immunocompromised hosts, patients are at risk not only of postherpetic neuralgia but also of severe local dermatomal infection (Rubin & Tolkoff-Rubin, 1983). Similarly, immunosuppressed patients are at increased risk for the development of disseminated cutaneous zoster and visceral dissemination. The higher the level of immunosuppression, the greater the risk of dissemination. Accordingly, prompt initiation of antiviral therapy with close follow-up is warranted for these patients, even if they have only superficial skin infection (3).

The level of serum lactate dehydrogenase is elevated in most patients with Pneumocystis pneumonia (>300 IU/mL). There is no diagnostic pattern exists for Pneumocystis pneumonia on routine chest radiograph that may be entirely normal or develop the classic pattern of perihilar and interstitial ground-glass infiltrates. Chest CT scans are more sensitive to the diffuse interstitial and nodular pattern than routine radiographs. The manifestations of P. carinii (jiroveci) pneumonia –both clinically and radiologically- are virtually identical to the manifestations of CMV and it is very difficult to determine whether both pathogens are present (Fishman & Davis, 2008).

Active infection of renal allografts has been associated with progressive loss of graft function (“BK nephropathy”) in approximately 4% of renal transplant recipients; this is referred to as polyomavirusassociated nephropathy (PVAN). The clinical presentation of disease is usually as sterile pyuria, reflecting shedding of infected tubular and ureteric epithelial cells. ” In some cases, Infectious Complications in Kidney Transplantation 19 the patient presents with diminished renal allograft function or with ureteric stenosis and obstruction (Fishman, 2002).

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After the Kidney Transplant - The Patients and Their Allograft by Jorge Ortiz, Jason André


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